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The
Martha's Vineyard Times is a weekly publication.
July 28 - August 3, 2005 Edition
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North Road: Uncoiling the double helix
July
28, 2005
By
Russell Hoxsie, M.D.
Milton and Virginia were old friends. We saw each other often. In
the old days we came and went in each others homes all the time.
They read or listened to books constantly and remembered most of what
they read. Each could quote poetry at the drop of a hat, some of it,
I think, neither one had seen or heard in years. Virginia was a particularly
good writer and critic. She had a career before she married, writing
radio scripts for dramas. Milton was a detail man, loved a good argument
or negotiation of a difficult conflict. Five years after Virginias
death he has attained serenity under thoughtful care at Long Hill
in Edgartown.
As they grew older they seemed ever more anxious to share with us
and often pressed upon us something of value to borrow with no thought
of return. Books had been their currency and thats what they
loaned out most. Several years ago while still in his own home, Milton
went to one of his bookcases and pulled out a faded 1960s edition
of James Watsons The Double Helix. Here,
he said to me, You must read this if you havent already.
I like it because of his humor. He tells a good story. Youll
like it too.
I nearly failed physics and chemistry in college. Returning to Wesleyan
as a senior from my tour in the Army, I had the awful luck to take
physics with the entering freshman. The professor told me I might
as well not apply to any of the good medical schools because of my
grade at the end of the year. Not only was I humiliated, but I was
pissed. I never could see the connection between the extravagant experiments
Professor Moth Eaton ran at the front of the amphitheater
with my future life as a healing physician. When I was accepted at
Cornell, I was tempted to throw a stink bomb in Eatons next
freshman class. In any case, Miltons generosity with Watsons
book brought back some of my old feelings of inadequacy, which were
still dormant not too far beneath my attempt to remain cool. It was
hard to say no as Milt opened a page to show me a picture of the young
Watson smiling in Stockholm receiving his Nobel Prize in Chemistry
in 1962 for discovering the molecular structure (a double helix) of
DNA. I took the book, opened it that night and read 25 pages without
enthusiasm or anything like an epiphany.
When are you going to return Miltons book? Mary
Ann asked. Every week or two it would be moved to dust the table and
she would repeat the question. You know youve had that
book a couple of months now. Youd better take it back.
Milton read that thing 30 years ago. He doesnt want it
right back. I still want to read it. Each time I said that,
I felt guilt, the guilt of a college boy failing in physics, the guilt
of a phony medical student having gotten into Cornell by some devious
means, the guilt of a modern doctor who didnt know beans about
DNA, let alone its complex physical structure. I had peeked at the
photograph of its model in the center of the damned book, which increased
the guilt of a little boy who had taken something from his father
on false pretenses without the slightest intention of following through
with a bargain.
I slept poorly some nights. I wondered why. One particular stretch
in June I began to tell the time by when the birds first chirped in
the morning. I knew it was only 4 am when the light was still absent
and the birds were quiet, except for a heron or gull down in the marsh.
I knew it was 10 minutes past four when the sky began to look the
slightest bit tinged with gray out the window. Of course I had to
make allowances for how close we were getting to the summer equinox.
I knew for certain it was 4:30 when the sparrows and the finches and
the mourning doves were calling for more thistle seed at the feeder
near our bedroom window. At the crack of waking, I count the number
of hours and minutes slept. My eyes cant yet focus on the hands
of the clock; has it been six hours or only five hours? Thats
not enough sleep. What am I going to do all day? I began thinking
of the after-lunch nap even before I put on my glasses to be sure
I had read the clock correctly. Ive been known to be a whole
hour off. I got up once at 5:30 and didnt realize the early
time until I overheard on Channel 10 from Providence an interview
between a minister and six prostitutes whom he was trying to lure
off the streets down around the Rhode Island Hospital. I never watch
early morning talk television before 6:30.
The answer, of course, to my insomnia was to take up that damnable
book. Id learn what James Watson did and what this DNA structure
was all about if it killed me. Besides, my doctor had told me never
to stay lying sleepless in bed. You know, dont you, shed
said to me while I perched on the end of her exam table, my sciatic
nerve screaming to be relieved off the table, you know, dont
you, that your brain stem regulates your sleep pattern and youre
teaching it to stay awake while youre lying there, thrashing
and turning about in the bed. Get up and teach it that awake is walking
or sitting in a chair, keeping your mind clear to read a book. Dont
watch TV though. The light stimulates your melatonin to turn off and
wakes you up for real.
So I took up Watson. I followed him from a lab in the States to a
lab at Cambridge, England. I was mildly scandalized by the looseness
with which he kept his contracts from the institutions funding his
grants to study abroad. I even allowed he was human enough to sin
having a good time in Paris and on the shores of the Mediterranean
where Science seemed far removed. I was shocked at the petty competitiveness
between him and Linus Pauling. Pauling the giant, Watson, the midget.
They actually concealed scientific data from one another, mostly Watson
hiding on Pauling. There were all kinds of intrigues. The leading
woman scientist in the saga of discovering the structure for DNA was
considered beneath contempt. Her work of years was denigrated, I thought,
by virtue of her inability to see the genius of Watsons theories
and calculations. No more of her x-ray diffraction data. Back to modeling
with Tinker Toys went the boys (Watson and friends). Finally the damn
model was finished to huzzahs from all the science crowd of the world.
Pauling was a disappointed man. He stands tall yet. He retained his
grace. The world goes on richer by far because the Tinker Toy hot
shots solved the puzzle. Watson rose like cream in a bottle.
Sleep returned after each hour of reading. I finished the book in
a week. I smiled. And finally, I could look Mary Ann in the eye and
tell her Id returned the book to Milton safely, as good as I
got it and I the better in more ways than one. |
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