Laugh with comedian Lenny Clarke and friends at Flatbread

From left: duo Otto and George; Lenny Clarke, and Bobby Slayton.

Comedian Lenny Clarke and three of his friends are bringing their topical, cutting-edge humor to a one-night Comedy Show of the Year this Sunday, August 4, at Flatbread Co. The colleagues are three of his favorite comedians — Bobby Slayton and the team of Otto and George, the dummy.

“Don’t come to the show expecting any politically correct humor,” Mr. Clarke told The Times in a phone call last week. “These guys are some of the funniest people I know.” All three have been headliners and active in the business for more than 30 years.

“We have 120 years of performing between us,” he said. “When we started there was no such thing as politically correct. There weren’t any rules. We don’t plan to hold anything back. This will be a funny show.

“These two guys are both on my list of top 10 favorite comedians. We never get to work together, so this is a special show.”

The group is on a small tour that has sold out every place they’ve played. The Vineyard show will be the final stop on a tour that included Providence and the Boston Strong benefit show at the end of May in Boston.

Mr. Clark has also been involved with One Fund Boston, formed to assist victims and families affected by the tragic events at the Boston Marathon, and he will perform for the Pan Mass Challenge, a cross-Massachusetts cycling fundraiser to fight cancer.

A Cambridge native and Chilmark resident, Mr. Clarke is a working comedian and actor. Starting out in Boston in the early 1980s, he wrote and starred in a local TV show, “Lenny’s Late Show.” His most recent TV gigs have been as Uncle Teddy on the FX channel series “Rescue Me,” and as Melvin Newman in NBC’s “Are You There, Chelsea,” based loosely on a book by Chelsea Handler.

Mr. Clarke brings his distinctive heavy Boston accent along with him, but he now calls the Vineyard home. “I only leave so I can make money to live here,” he said. He said he knows he is still just a wash-ashore even though he bought a house in Chilmark about 17 years ago. “I bought the house because they wouldn’t let me on Lucy Vincent Beach,” he said.

Often called a comic’s comic and the pit bull of comedy, Bobby Slayton performs his own intense style of stand-up comedy. He has had roles in the movies “Get Shorty,” “Ed Wood,” “Bandits,” “Dreamgirls,” and has been on “The Tonight Show,” “Politically Incorrect,” and HBO’s “Comic Relief,” and his own stand-up special. He was also a regular on the HBO series “Mind of a Married Man,” and his distinctive gravelly voice has often been heard on animated shows like “Dr. Katz” and “Family Guy.”

Otto Petersen and his dummy George Dudley are the adult-themed ventriloquist comedy team Otto and George. Otto has appeared on “Late Show with David Letterman,” “The Howard Stern Show,” and more.

Lenny Clarke and Friends featuring Bobby Slayton, Otto and George, Sunday, August 4, 9 pm, Flatbread Co., Edgartown (M.V. Airport). $35; $30 in advance. 21+. For more information, visit